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艾纳香化学成分的研究

Study on the Chemical Constituents of Blumea balsanifera DC.

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【作者】 梁会曹佩雪邱净英李霞柴立梁光义

【Author】 LIANG Hui1,2,CAO Pei-xue2,QIU Jing-ying 2,LI Xia3,CHAI Li3,LIANG Guang-yi 2(1.Guiyang College of Traditional Chinese Medicine,Guizhou,Guiyang 550002 China;2.The Key Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academy of Science,Guiyang,Guizhou 550002 China;3.Guizhou Holy Pharmaceutical Co.,Ltd.,Guiyang 550018 China)

【机构】 贵阳中医学院贵州省中国科学院天然产物化学重点实验室贵州宏宇药业有限公司

【摘要】 目的研究艾纳香Blumea balsanaferaDC.的化学成分。方法采用硅胶柱色谱、薄层色谱、Sephadex LH-20柱色谱等方法分离纯化化合物,利用核磁共振等现代波谱技术解析化合物结构。结果从艾纳香的醋酸乙酯、氯仿部分分离得到7个化合物,鉴定为艾纳香素(blumeatin,1)、花椒油素(xanthoxylin,2)、木犀草素(luteolin,3)、胡萝卜苷(dau-costerol,4)、槲皮素(quercetin,5)、帕得马亭(padmatin,6)、3,5,5′,7-四羟基黄烷酮(3,5,5′,7-tetrahydroxyflavanone,7)。结论除化合物1和5外,其余5个化合物均为第1次从艾纳香中获得。

【Abstract】 Objective To study the chemical constituents of Blumea balsanifera DC.Methods The compounds were isolated and repeatedly purified by silica gel column chromatography,TLC,Sephadex LH-20 column chromatography,and their structures were elucidated on the basis of physico-chemical constants and spectral analysis.Results Seven compounds were obtained and elucidated as blumeatin(1),xanthoxylin(2),luteolin(3),daucosterol(4),quercetin(5),padmatin(6),3,5,5′,7-tetrahydroxyflavanone(7).Conclusion The compounds 2,3,4,6 and 7 were isolated from this genus for the first time.

【关键词】 艾纳香化学成分黄酮
【Key words】 Blumea balsanifera DC.Chemical studiesFlavanoids
【基金】 国家“973”计划前期研究专项(No.2007CB516813);贵州省科技创新人才团队专项资金黔科合人才团队专项资金(No.[2008]4008);贵州省重点实验室项目(黔科合计Z字[2009]4005)
  • 【文献出处】 时珍国医国药 ,Lishizhen Medicine and Materia Medica Research , 编辑部邮箱 ,2011年02期
  • 【分类号】R284.2
  • 【被引频次】37
  • 【下载频次】785
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