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EB病毒VCA-IgA在鼻咽癌筛查中的临床意义
Clinical Significance of EB-VCA-IgA in Nasopharyngeal Carcinoma Screening
【摘要】 目的探讨血清EB病毒衣壳抗原(EB-VCA IgA)在鼻咽癌筛查的临床意义。方法以2009年7月-2011年6月期间在本院进行EB-VCA IgA筛查的3 820例居民为研究对象,用酶联免疫吸附法测定血清EB-VCA IgA;对结果异常者取鼻咽部黏膜脱落细胞或活体组织检查,分析EB-VCA IgA在鼻咽癌筛查中的意义。结果在3 820例居民中,EB病毒抗体阳性48例(1.26%),确诊为鼻咽癌2例。结论在鼻咽癌的高发地区,EB-VCA IgA可作为一项常规防癌检查项目,以有利于鼻咽癌的早期发现、早期诊断、早期治疗。
【Abstract】 Objective To investigate the clinical significance of serum EB virus capsid antigen(EB-VCA IgA) in nasopharyngeal carcinoma screening. Methods Taking 3,820 cases residents who have EB-VCA IgA screening in our hospital July 2009-June 2011 period as study population,enzyme-linked immunosorbent assay of serum EB-VCA IgA,abnormal results obtained nasopharyngeal mucosa cytology or biopsy,and analysis the significance of EB-VCA IgA in nasopharyngeal carcinoma screening. Results Of 3,820 cases residents,48 cases(1.26%) EB virus antibody positive,2 cases diagnosed nasopharyngeal carcinoma. Conclusions In the area of high incidence of nasopharyngeal carcinoma, EB-VCA IgA can as a routine anti-cancer inspection program,in order to facilitate the earlier detection,earlier diagnosis and earlier treatment of nasopharyngeal carcinoma.
【Key words】 EB virus; EB-VCA IgA; Nasopharyngeal carcinoma; Screening;
- 【文献出处】 实用预防医学 ,Practical Preventive Medicine , 编辑部邮箱 ,2011年12期
- 【分类号】R739.63
- 【被引频次】6
- 【下载频次】275