【摘要】 目的探讨支气管肺炎伴外周血血小板计数增高(ST)患儿潮气呼吸肺功能的改变。方法比较28例支气管肺炎伴血小板增多的患儿(A组)与33例支气管肺炎血小板计数正常的患儿(B组)的潮气呼吸肺功能。结果 A组代表小气道阻塞的肺功能指标呼气达峰时间(tPTEF)、达峰时间比(呼气达峰时间/呼气时间,tPTEF/tE)、剩余25%潮气量时的呼气流速(TEF25)、剩余25%潮气量时的呼气流速/呼气峰流速(TEF25/PTEF)较B组显著降低(均P<0.01),且tPTEF/tE、TEF25与血小板计数成负相关(r分别为-0.461、-0.407,均P<0.05)。代表通气功能的每公斤潮气量(VT/kg)指标两组差异无统计学意义(P<0.05)。结论肺炎伴血小板增多患儿小气道阻塞程度较血小板计数正常者严重,外周血血小板计数可作为预测支气管肺炎患儿小气道阻塞程度的有效指标之一。更多还原

【Abstract】 Objective To explore the changes of tidal pulmonary function in paediatric patients with thrombocytosis in bronchopneumonia.Methods Twenty eight patients with thrombocytosis in bronchopneumonia(group A) were measured and recorded the lung function parameters by V26 max pulmonary function testing(PFT)machine.Campared with agematched 33 patients with nomal platelet counts in bronchopneumonia(group B).Results Compared with group B,the lung function parameter including time of peak tidal expiratory flow(tPTEF),the ratio of exhaled time at PTEF to total expiratory time(tPTEF/tE),tidal expiratory flow at 25% of the remaining tidal volume(TEF25)and the ratio of TEF25 to PTEF(TEF25/PTEF %)decreased in group A.The difference between the two groups was statistically significant(P<0.01).The platelet count with two kinds of pulmonary function parameters(tPTEF/tE,TEF25)was negatively correlated.(r=-0.461,r=-0.407,P<0.05).Conclusion The severity of pulmonary function damage in pneumonia in chidren is associated with the platelet count.The platelet count is a useful clinical marker in judging the degree of small airway obstruction in pneumonia.更多还原