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依达拉奉联合克林澳治疗急性脑梗死的疗效观察
Treatment Efficacy of Edaravone and Kelin’ao on Acute Cerebral Infarction
【摘要】 目的观察依达拉奉联合克林澳(马来酸桂哌齐特)注射液治疗急性脑梗死的临床疗效。方法选择2009年1月—2011年2月在我院神经科住院的200例急性脑梗死患者,随机分为治疗组(100例)及对照组(100例)。两组患者除给予常规治疗外,治疗组给予依达拉奉注射液30mg,2次/d及克林澳注射液320mg,1次/d;对照组100例给予依达拉奉注射液30mg,2次/d。两组患者均治疗14d,观察两组治疗前后疗效、神经功能缺损评分和欧洲脑卒中评分量表(ESS)评分的变化并进行对比分析。结果两组患者治疗后临床疗效、神经功能缺损评分和ESS评分的变化差异有统计学意义(P<0.05)。结论依达拉奉联合克林澳注射液治疗急性脑梗死的疗效肯定,能明显改善神经功能的损伤,是一种安全有效的方法,值得临床推广应用。
【Abstract】 Objective Treatment Efficacy of Edaravone and Kelin’ao on Acute Cerebral Infarction.Methods Choose January 2009 February 2011 in our hospital neurologist 200 patients with acute cerebral infarction patients,randomly divided into the treatment group(100 cases) and the control group(100 cases).Two groups of patients except give routine therapy,the treatment group 100 patients outside to 30mg edaravone injection,2 times/d and Kelin’ao.Results Two groups of patients after treatment,efficacy and neural function defect scale and the difference of ESS score was statistically significant(P<0.05).Conclusion Edaravone in treatment of acute joint Kelin’ao injection,the clinical curative effect of cerebral infarction affirmation,can significantly improve functional neurological damage,is a safe and effective method of clinical application.
【Key words】 Cerebral infarction; Edaravone; Kelin’ao; Free radical scavenging agents;
- 【文献出处】 实用心脑肺血管病杂志 ,Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease , 编辑部邮箱 ,2011年09期
- 【分类号】R743.3
- 【被引频次】4
- 【下载频次】40