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依达拉奉辅助治疗急性脑出血91例疗效分析

Analysis on effect of edaravone as adjuvant treatment in 91 cases of acute cerebral hemorrhage

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【作者】 练启辉

【Author】 LIAN Qi-hui.Shenzhen Longgang District Dapeng People’s Hospital.Shenzhen Guangdong 518120,China

【机构】 深圳市龙岗区大鹏人民医院神经内科

【摘要】 目的观察依达拉奉注射液辅助治疗急性脑出血患者的临床疗效。方法将91例急性脑出血患者随机分为对照组(n=45)和观察组(n=46),两组均给予基础治疗,观察组在对照组基础上给予依达拉奉治疗方案。比较治疗前后两组患者血肿体积、水肿体积、神经功能缺损评分及总有效率等指标。结果与治疗前相比,治疗后两组血肿、水肿体积均显著减少,神经功能缺损评分显著减低;而观察组上述指标改善程度及总有效率均显著高于对照组,结果均具有统计学意义(P<0.05)。结论依达拉奉辅助治疗急性脑出血,有利于血肿的吸收及周围水肿的减轻,改善患者生活质量,值得临床广泛推广。

【Abstract】 Objective To observe the clinical effect of edaravone injection as adjuvant treatment for patients with acute cerebral hemorrhage.Methods Ninety one patients with acute cerebral hemorrhage were randomly divided into control group(n=45) and observation group(n=46).Patients in both groups were provided with primary treatment for cerebral hemorrhage,and patients in observation group were additionally given with edaravone.The indexes such as hematoma volume,edema volume,neurologic impairment scores and total effective rates of patients in these two groups were compared before and after the treatment.Results The hematoma volume and edema volume in patients of both groups were significantly reduced after treatment and the neurologic impairment scores were significantly decreased after treatment.The scale of improvement in such indexes and the total effective rate in patients of observation group were distinctively higher than those of patients in control group,and the difference was statistically significant(P<0.05).Conclusion Edaravone in treatment of patients with cerebral hemorrhage caused by hypertension can be helpful in absorption of hematoma and remission of peripheral edema as well as improvement of the life quality of patients.Therefore it is worthy to be extensively recommended for clinical application.

  • 【文献出处】 临床和实验医学杂志 ,Journal of Clinical and Experimental Medicine , 编辑部邮箱 ,2011年16期
  • 【分类号】R743.3
  • 【被引频次】2
  • 【下载频次】18
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