【摘要】 目的探讨晚期恶性梗阻性黄疸并发消化道出血的高危因素,提出预防及治疗措施。方法回顾分析我科2008年12月至2010年12月我科收治晚期恶性梗阻性黄疸并发消化道出血患者35例,分析引起消化道出血的相关因素、出血表现和治疗结果。结果晚期恶性梗阻性黄疸并发消化道出血的高危因素是内毒素血症、低蛋白血症、肾功能损害、凝血功能障碍。晚期恶性梗阻性黄疸引起消化道出血病情危重,临床止血率低,本组成功止血率42.9%。结论积极加强营养、预防和控制内毒素血症是预防晚期恶性梗阻性黄疸上消出血的关键;抑制胃酸、静脉输注止血药及生长抑素是治疗上消出血的重点。更多还原

【Abstract】 Objective To study the high risk factors for gastrointestinal hemorrhage in patients with malignant obstructive jaundice,and to propose the measures for its prevention and treatment.Methods The data of thirty five cases of late stage malignant obstructive jaundice complicated with gastrointestinal hemorrhage admitted in this hospital during December 2008 to December 2010 were retrospectively reviewed and analyzed for relevant factors,manifestations of hemorrhage and the outcome of treatment.Results The high risk factors for gastrointestinal hemorrhage in patients with late stage malignant obstructive jaundice were endotoxemia,hypoproteinemia,renal function impairment and blood coagulation disorders.Gastrointestinal hemorrhage complicated in patients with late stage malignant obstructive jaundice was critical with low clinical hemostatic rate.The successful rate of hemostasis was 42.9%.Conclusion Strengthening nutritional supply,and prevention and control blood coagulation disorders are key points for prevention of gastrointestinal hemorrhage;and measures for reducing gastric acid,venoclysis of hemostatics and somatostatin are important in controlling gastrointestinal hemorrhage.更多还原