【摘要】 采用固相共研磨法和饱和水溶液法合成β-环糊精和克百威的包合物,通过红外、紫外和荧光光谱对其结构和性质进行了表征;利用紫外光谱研究了不同浓度下β-环糊精溶液对克百威溶解度的影响,绘制出相溶解曲线图以确定β-环糊精和克百威之间形成物质的量比为1∶1的包合物。利用克百威的内源荧光特性,根据包合前后以及在不同温度下荧光强度变化,结合Stern-Volmer方程,获取不同温度下β-环糊精和克百威之间的结合常数Kc;热动力学方法研究温度对包合反应的影响,根据热力学参数得出包合反应是自发熵和焓共同驱动过程。更多还原

【Abstract】 The inclusion compounds of carbofuran with β-cyclodextrin(β-CD) were prepared by kneading method and aqueous-solution method.The properties of the compound were investigated by FT-IR spectra,UV-vis spectra and Fluorescence spectra.The solubility of carbofuran in aqueous solution increased in the presence of β-cyclodextrin due to complex using UV-spectrophotometric measurements.The results show that 1∶1 inclusion complexes are formed between β-CD and carbofuran.The intrinsic fluorescence of carbofuran can be enhanced by β-CD.The binding constants are obtained according to the Stern-Volmer equation.The corresponding thermodynamic parameters ΔH,ΔG and ΔS are calculated.Their values suggested that enthalpy and entropy are the main driving force for the inclusion reaction.更多还原