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胃肿瘤64层螺旋CT灌注成像的初步研究

Preliminary Evaluation of 64-slice Spiral CT Perfusion Imaging in Stomach Neoplasm

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【作者】 李攀高剑波岳松伟张永高杨学华

【Author】 LI Pan;GAO Jianbo;YUE Songwei;ZHANG Yonggao;YANG Xuehua;Department of Radiology,the First Affiliated Hospital of Zhengzhou University;

【通讯作者】 高剑波;

【机构】 郑州大学第一附属医院放射科CT室

【摘要】 目的 探讨64层螺旋CT胃灌注成像在胃癌及胃间质瘤诊断及鉴别诊断中的临床应用价值。方法 对经手术病理证实的73例胃癌及43例胃间质瘤患者行64层螺旋CT灌注成像扫描,经ADW4.3工作站处理,得出相关灌注参数及灌注图像,并进一步分析不同分化程度胃癌及胃间质瘤与其灌注参数之间的关系。结果 胃癌灌注参数:血流量(BF)、血容量(BV)、平均通过时间(MTT)、表面通透性(PS)值分别为(121.6±61.06) ml·100 g-1·min-1,(10.45±7.09) ml/100 g,(6.89±3.59) s,(26.31±14.99) ml·100 g-1·min-1;良性胃间质瘤灌注参数BF、BV、MTT、PS值分别为(77.28±25.57) ml·100 g-1·min-1,(7.91±2.84) ml/100 g,(7.37±2.38) s,(13.99±4.06) ml·100 g-1·min-1;恶性胃间质瘤灌注参数BF、BV、MTT、PS值分别为(95.13±29.75) ml·100 g-1·min-1,(8.21±2.65) ml/100 g,(7.33±1.83)s,(14.15±4.04) ml·100 g-1·min-1。不同分化程度胃癌(分化组与未分化组)灌注参数值PS差异有统计学意义(P<0.01);不同分化程度胃间质瘤(良性与恶性)灌注参数BF、BV、MTT、PS值差异均无统计学意义(P>0.05);胃癌与恶性胃间质瘤灌注参数BF、MTT、PS值差异有统计学意义(P<0.05)。结论 64层螺旋CT灌注成像对于进一步明确胃癌及胃间质瘤的诊断及鉴别诊断具有较大的临床应用价值,并对其治疗及预后方面有一定指导意义。

【Abstract】 Objective To evaluate the value of 64-slice CT perfusion in diagnosing gastric carcinoma and gastric stromal tumor(GST).Methods Seventy-three cases with gastric carcinoma and 43 cases with GST confirmed by pathology underwent 64-slice spiral CT perfusion imaging.All the CT data were transferred to ADW4.3 workstation and calculated.The relationship of CT perfusion data between gastric carcinoma and GST was evaluated.Results The perfusion parameters including BF,BV,MTT and PS were(121.6±61.06) ml·100 g-1·min-1,(10.45±7.09) ml/100 g,(6.89±3.59) s,(26.31±14.99) ml·100 g-1·min-1 in the group of gastric carcinoma.(77.28±25.57) ml·100 g-1·min-1,(7.91±2.84) ml/100 g,(7.37±2.38) s and(13.99±4.06) ml·100 g-1·min-1 in benign GST,(95.13±29.75) ml·100 g-1·min-1,(8.21±2.65) ml/100 g,(7.33± 1.83) s and(14.15±4.04) ml·100 g-1·min-1 in malignant GST,respectively.The perfusion parameter of PS had statistical significance between differentiated gastric carcinoma and undifferentiated gastric carcinoma.There was not statistical significance in BV,BF and MTT between benign gastric stromal tumor and malignant gastric stromal tumor.The perfusion parameters of BF,MTT and PS had statistical significance between gastric carcinoma and malignant heoplasm gastric stromal tumor.Conclusion 64-slice spiral CT perfusion plays a key role in the diagnosis and differential diagnosis of gastric.

  • 【文献出处】 实用放射学杂志 ,Journal of Practical Radiology , 编辑部邮箱 ,2011年04期
  • 【分类号】R735.2;R730.44
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