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18F-FDG PET/CT显像在肾上腺肿瘤诊断中的应用

Application of 18F-FDG PET/CT in the diagnosis of adrenal tumor

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【作者】 叶慧李杨莫逸谢爱民彭翔

【Author】 YE Hui1,LI Yang2,MO Yi1,XIE Aimin1,PENG Xiang11PET/CT Center,Hunan Tumor Hospital,Hunan Changsha 410013,China;2Department of Urology,Xiangya Hospital,Central South University,Hunan Changsha 410008,China

【机构】 湖南省肿瘤医院PET/CT中心中南大学湘雅医院泌尿外科

【摘要】 目的:评价18F-脱氧葡萄糖(18F-fluorodeoxyglucose,18F-FDG)PET/CT显像在肾上腺肿瘤诊断中的应用价值。方法:回顾性分析42例肾上腺肿瘤患者的全身18F-FDG PET/CT及CT平扫加增强的影像学资料,比较两者对肾上腺肿瘤的诊断价值。结果:42例中,原发性肾上腺肿瘤30例,均经手术病理证实。其余12例为转移性肾上腺肿瘤,肾癌转移4例,肺癌转移7例,肝癌转移1例。18F-FDG PET/CT检查阳性42例,敏感度100%,良性病变的SUV值为1.1-2.6,平均1.8,恶性病变的SUV值为2.5-12.3,平均6.0。良恶性病变的SUV值差异有统计学意义(P<0.01)。CT平扫加增强检查阳性38例,敏感度90.5%。PET/CT对肾上腺肿瘤的敏感度明显高于CT,两者差异有统计学意义(P<0.05)。结论:18F-FDG PET/CT在肾上腺肿瘤诊断中具有重要价值,敏感度高于CT。

【Abstract】 Objective:To evaluate the clinical role of F-18 fluorodeoxyglucose(FDG)-positron emission tomography(PET) in the diagnosis of adrenal disease.Methods: 18F-FDG PET/CT was performed retrospectively in 42 cases with adrenal tumor and compared with CT.Results: Of 42 cases,30 cases were primary adrenal tumors confirmed by surgery and pathology.12 cases were metastasistic adrenal tumors.The primary focus were kidney cancer(4 cases),lung cancer(7 cases) and liver cancer(1 case).The sensitivity of 18F-FDG PET/CT and CT imaging were 100%,90.5%.A statistic difference in standardized uptake value was found between the benign and malignant lesions(P<0.01).Conclusion: The sensitivity of 18F-FDG PET/CT possesses super sensitivity for the diagnosis of adrenal tumors comparing with CT.It may have an important role in the diagnosis of adrenal tumor.

【关键词】 PET/CT肾上腺肿瘤CT
【Key words】 PET/CTadrenal tumorcomputed tomography
  • 【文献出处】 现代肿瘤医学 ,Journal of Modern Oncology , 编辑部邮箱 ,2011年11期
  • 【分类号】R736.6
  • 【被引频次】3
  • 【下载频次】163
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