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内镜窄带成像(NBI)对癌前病变肠上皮化生的诊断价值

Diagnostic value of endoscopic narrow-band imaging(NBI) in pre-cancerous intestinal metaplasia

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【作者】 马桂凤张国梁华建平李俊美刘静

【Author】 MA Gui-feng,ZHANG Guo-liang,HUA Jian-ping,LI Jun-mei,LIU Jing Department of Digestive,Tianjin First Central Hospital,Tianjin 300192,China

【机构】 天津市第一中心医院消化科

【摘要】 目的:探讨内镜窄带成像(NBI)对萎缩性胃炎癌前病变胃肠上皮化生(GIM)的诊断价值。方法:对62例慢性胃炎患者予以内镜常规检查后启动NBI系统,在NBI下如发现淡兰色嵴样结构,在此处取活检,如无此结构就在可疑GIM部位及胃窦前、后壁、大弯、小弯4个部位取活检,并与病理组织学结果进行对照。结果:经病理组织学结果证实,内镜NBI下GIM总检出率为(50/62)80.65%,淡兰色嵴样结构诊断GIM的阳性预测值为91.86%,阴性预测值为84.09%,敏感性为84.95%,特异性为91.36%。结论:内镜窄带成像观察淡兰色嵴样结构是一个GIM高度精确标志,NBI可以提高GIM的检出率,对胃癌的早期诊断及治疗具有重要意义。

【Abstract】 Objective:To study the diagnostic value of endoscopic narrow-band imaging(NBI) to atrophic gastritis precancerosis gastric intestinal metaplasia(GIM).Methods:Sixty two patients were examined by use of a NBI endoscopy,if to discover light blue ridge structure then take biopsy;if no light blue ridge structure biopsy was made in suspicious GIM parts and gastric antrum before and after,lesser curve,greater curve.Results:The endoscopic diagnostic result was compared with pathologic result.Total detection rate of GIM was(50/62) 80.65%.The appearance light blue ridge structure correlated with GIM with sensitivity of 84.95%,specificity of 91.36%,positive predictive value of 91.86%,negative predictive value of 84.09%.Conclusion:Endoscopic narrow-band imaging observe the light blue ridge structure is a highly accurate sign of the presence of GIM.NBI can improve the detective rate of GIM.In early diagnosis and treatment of cancer of the stomach is of important significance.

  • 【文献出处】 现代肿瘤医学 ,Journal of Modern Oncology , 编辑部邮箱 ,2011年02期
  • 【分类号】R735.2
  • 【被引频次】17
  • 【下载频次】276
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