【摘要】 目的:观察吉西他滨联合表柔比星方案治疗转移性肝癌的疗效。方法:吉西他滨1000mg/m2,静脉滴注,30分钟滴完,第1,8天;表柔比星60mg/m2,静脉推注,第1天,21天为一周期。连用2-3周期。结果:45例可评价疗效患者,共化疗113个周期,肿瘤完全缓解(CR)0例,部分缓解(PR)34例,稳定(SD)7例,进展(PD)4例。总有效率为64.4%,其中鼻咽癌肝转移有效率为66.7%,胰腺癌肝转移有效率为83.3%,乳腺癌肝转移有效率80%,非小细胞性肺癌肝转移有效率52.9%,胃癌肝转移有效率62.5%。结论:吉西他滨联合表柔比星治疗转移性肝癌,是安全有效的,尤其是胰腺癌及乳腺癌肝转移疗效尤为显著。更多还原

【Abstract】 Objective:To observe the effect of gemcitabine combinded with epirubicin in the treatment of metastatic liver cancer.Methods:Gemcitabine 1000mg/m2intravenously,30 minutes,at the day;Epirubicin 60mg/m2 intravenously at the first day.A course of treatment included 21 days.Results:Among 45 patients,altogether completed chemotherapy 113 cycles,CR 0,PR 34,SD 7,PD 4 cases.The total effectivrate was 64.4%,in which nasopharyngeal-cancer liver shifts metastasis effectivene rate was 66.7%,from pancreas was 83.3%,breast cancer 80%,non-small cell lung cancer 52.9%,stomach-cancer 62.5%.Conclusion:Gemcitabine combined with epirubicin treatment of mctastatic liver cancer,is safe and effective,particular in the cancer of the pancreas and breast cancer.更多还原