【摘要】 目的:探讨磷酸肌酸钠对急性冠脉综合征患者的临床预防和治疗作用。方法:选取120例急性冠脉综合征患者,59例行常规治疗,包括给氧、抗血小板、抗凝、扩张冠脉、营养心肌、止痛等。61例患者在常规治疗的基础上加用磷酸肌酸钠1g,静脉滴注,1次/d,共7d。结果:①使用磷酸肌酸钠的急性冠脉综合征病人较未使用的心律失常的发生率明显降低;②使用磷酸肌酸钠的急性心肌梗死病人较未使用的血清磷酸肌酸激酶(CK)及M B同功酶明显降低;③未用磷酸肌酸钠的急性冠脉综合征病人较使用的心功能明显减低;④使用磷酸肌酸钠的急性冠脉综合征病人较未使用的节段性室壁运动异常的发生率明显减少。结论:磷酸肌酸钠能显著改善急性冠脉综合征患者的心肌代谢、减轻心肌损伤、保护心功能、减少心律失常等并发症的发生。更多还原

【Abstract】 Objective: To investigate clinical action of creatine phosphate on the acute coronary syndrome(ACS) patients.Methods: One hundred and twenty ACS patients were allocated into two groups which was treated with routine therapy(59 cases) and routine theropy plus creatine phosphate(61 cases) 1g intravenous drip once-daily for 7 days.Results: The patients treated with creatine phosphate have less onset of arrhythmia,lower blood concentration of creatine kinase(CK) and CK-MB,better cardiac function and less abnormal local ventricular wall motion.Conclusion: Creatine phosphate can improve myocardial metabolism,relieve myocardial injury and inhibit appearance of arrhythmia.更多还原