【摘要】 量子点是一种新兴的半导体荧光材料,耐光漂白,激发光谱宽,发射光谱可调。将量子点应用于生物医学检测领域,可以解决传统有机染料发光时间短、不能同时多色检测等问题。水溶性量子点结合特定的生物分子后可以标记待测目标,用于生物分子的分析检验和细胞标记、组织层次成像分析,并能参与荧光共振能量转移(FRET)检测。将量子点与芯片技术结合,开发集成、便捷、高灵敏度的多种肿瘤标志物诊断技术,可能成为量子点用于临床实践的方向之一。更多还原

【Abstract】 Semiconductor quantum dots(QDs) are a new kind of biological fluorescence material,which has many advantages,such as broad excitation spectra,tunable emission spectra and good photostability.In the field of biomedical detection,the problems encountered in the traditional organic dye-based biomedical detections,such as short florescence lifetime and failure to simultaneous excitation of multiple colors,can be solved by using QDs.Water-soluble QDs combined with specific bio-molecules can label targeting bio-compound,which is useful in bio-molecule detection,cell labeling,tissue imaging,and can be used in fluorescence resonance energy transfer(FRET) technology.Combining QDs and protein chip technology to develop a new technology to detect multiple kinds of tumor markers will be one of the promising clinical applications of QDs with greater sensitivity,specificity,rapidity and convenience.更多还原