【摘要】 本文采用溶胶凝胶法制备含银抗菌液,用液体稀释法测定其对白色念珠菌(C.a)和金黄色葡萄球菌(S.a)的最低抑菌浓度(MIC),将抗菌液涂层到软衬材料表面后观察膜层厚度及表面形貌;用贴膜法测定其抑菌率。结果含银抗菌液能在义齿软衬材料表面成膜,不影响义齿的适合性。0.64 mg/ml浓度的抗菌液24 h涂层的抑菌率,C.a为90.82%,S.a为94.96%,能达到较好的抑菌效果。本文制备了含银抗菌液,选择合适的浓度在义齿软衬材料表面形成抗菌涂层,含银抗菌液能赋予义齿软衬材料表面良好的抗菌性,且不影响原软衬的适合性,具有一定临床应用价值。更多还原

【Abstract】 We tried to find the effects of the application of the antibacterial solution containing silver ions on the surface of the denture soft lining material.We selected the right concentration of the silver-containing solution and coated a soft lining material with the solution so that the soft lining material could be antibacterial.The antibacterial solution containing silver ions was prepared by sol-gel method.MIC of C.a and S.a were tested by broth dilution test.The surface property and thickness were tested after coated.The in vitro antibacterial ratio against C.a and S.a were demonstrated by the method of plate-counting.A film was formed after coating,while the adequacy was not changed.Antibacterial ratio of 0.64 mg/ml group against C.a was 90.82%,and that against S.a was 94.96% in 24 hours,respectively.It was found that the antibacterial property of the soft lining material can be acquired by coating this antibacterial solution with silver ion,without changing the adequacy.更多还原