【摘要】 目的:探讨改善妊娠期肝内胆汁淤积症患者围生结局及围生儿预后的方法。方法:对2006年3月-2011年3月在我院住院分娩的256例ICP患者及从我院住院无并发症正常分娩的10112个患者中随机抽取的256例患者的产检情况、分娩方式、围生儿结局进行回顾性分析。结果:ICP组与对照组在分娩方式、产后出血、早产、新生儿窒息、羊水粪染、围产儿死亡等方面比较差异均具有统计学意义(P<0.05);产检组与未检组在产后出血、早产、新生儿窒息、羊水粪染、围产儿死亡等方面比较差异有统计学意义(P<0.05)。结论:妊娠期肝内胆汁淤积症可增加早产、胎儿宫内窘迫、新生儿窒息、产后出血发生率,重视产前检查和孕期保健,对ICP患者做到早发现、早诊断、早治疗,选择适当分娩方式、适时终止妊娠,对改善围生结局及围生儿预后有积极的意义。更多还原

【Abstract】 Objective: To investigate the improvement of the perinatal outcomes and perinatal children of ICP.Methods: The clinical data of 256 cases of ICP and 256 cases of normal labor were analyzed retrospectively.Results: Compared the mode of delivery,postpar-tum hemorrhage,premature birth,neonatal asphyxia,meconium-stained amniotic fluid,perinatal death of the ICP group with the control group,the diferences were statistically significant(P<0.05).Compared the mode of delivery,neonatal asphyxia,perinatal death of chil-dren of the Prenatal group with the unprenatal group,the diferences were statistically significant(P<0.05).Conclusion: Impact of ICP on outcome of pregnancy,especially on perinatal children was great,and the prenatal care to improve perinatal outcomes and perinatal prog-nosis in children has a positive meaning.更多还原