【摘要】 自身免疫性疾病在人群中感染率5-10%,具有明显的性别差异,女性患者显著高于男性,具体机制仍未研究清楚。研究发现,除了机体自身的遗传易感体质外,雌激素,微嵌合体和性染色体都与自身免疫性疾病发病有关。更多还原

【Abstract】 Autoimmune diseases are estimated to affect 5-10% of the population with a significant female predominance reported for most of them.The mechanism of this sex bias remains unclear.Including a susceptible genetic background,autoimmune diseases are expected to be associated with estrogen,microchimerism and sex chromosome.更多还原