【摘要】 目前,模式动物秀丽线虫已被广泛应用于环境暴露评价和环境毒理学研究中。在系统介绍了各种秀丽线虫转基因品系在环境暴露与毒性评价以及环境毒理研究中的应用进展基础上,分析了秀丽线虫转基因品系在环境暴露与毒性评价研究中的灵敏性与直观性的特点。最后,讨论了秀丽线虫转基因品系在环境暴露与毒性评价以及环境毒理研究中尚存在的问题和可能的解决策略。更多还原

【Abstract】 So far,Caenorhabditis elegans as a model animal has been widely used in the studies on environmental exposure evaluation and environmental toxicology.In this review,the recent progresses in the application of transgenic strains of Caenorhabditis elegans for studies on environmental exposure evaluation and environmental toxicology were systematically introduced.The characteristics of being sensitive and directly visualized,which are the main characteristics of transgenic strains of Caenorhabditis elegans in toxicity evaluation of environmental exposure,were analyzed.On this basis,the questions needed to be solved and the suggestions for solutions were discussed so as to make better applications of transgenic strains of Caenorhabditis elegans in environmental exposure evaluation and environmental toxicology.更多还原