【摘要】 目的:研制魔芋粉片剂。方法:在用单因素实验选择崩解剂和填充剂的基础上,采用以硬度和崩解时限为指标的正交实验设计确立最佳配方。结果:选用8%羧甲基淀粉钠(CMS-Na)、0.3%硬脂酸镁、3%聚维酮K30、30%可压性淀粉(PCS),所得片剂崩解性能优良,各项指标均符合《中国药典》2005版相关规定。更多还原

【Abstract】 Objective:To prepare konjac flour tablets.Method:Design single factor tests to compare different disintegrants and filler.Then,disintegration time and hardness as index,the formulation of konjac flour tablets was optimized by orthogonal design test.Results:The optimized konjac flour tablets,which were prepared by selecting 8% CMS-Na,0.3% magnesium stearate,3% K30,30% PCS.The disintegration of above formulation was excellent,and all its indexes were conformed to the requirement of China Pharmacopoeia.更多还原