【摘要】 目的:探讨诺丽果汁对老龄小鼠抗氧化功能的影响。方法:老龄动物模型法,采用5、10、30mL/kg·bw剂量的诺丽果汁给老龄小鼠灌胃,于末次给药后,分别测定血中丙二醛(MDA)的含量和肝组织中超氧化物歧化酶(SOD)、谷胱甘肽过氧化物酶(GSH-Px)的活力。结果:与空白老龄对照组比较,诺丽果汁5、10、30mL/kg·bw剂量组能显著提高肝组织中SOD、GSH-Px活力,降低血中过氧化脂质MDA含量。结论:诺丽果汁具有抗氧化功能。更多还原

【Abstract】 Objective:To research the anti-oxidative activity of Noni juice in aged mice.Method:Tahitian Noni juice(TNJ)was administrated by gavage[5,10,30mL/(kg·bw)] to male mice(10-month-old CL ICR)for 30d.The mice were then sacrificed,and the blood and the livers were collected.The concentration of malondialdehyde(MDA)in the blood and the level of superoxide dismutase(SOD)and glutathione peroxidase(GSH-Px)in the liver were then measured by spectrophotometry.Result:TNJ produced a dose-dependent decrease of MDA,at the same time a dose-dependent increase of SOD and GSH-Px at all three doses.Conclusion:TNJ had antioxidant activity by protecting body against free radical-induced damage.更多还原