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植物microRNA对重金属胁迫响应的调控

Regulation of Heavy Metal Stress Response by Plant microRNAs

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【作者】 丁艳菲朱诚王珊珊刘海丽

【Author】 DING Yan-Fei1,2),ZHU Cheng2,1),,WANG Shan-Shan1),LIU Hai-Li2) (1) State Key Laboratory of Plant Physiology and Biochemistry,College of Life Sciences,Zhejiang University,Hangzhou 310029,China;2) College of Life Sciences,China Jiliang University,Hangzhou 310018,China)

【机构】 浙江大学生命科学学院浙江大学植物生理学与生物化学国家重点实验室中国计量学院生命科学学院

【摘要】 <正>镉是重要的重金属污染物,它严重影响植物生长,并危害人体健康.植物的重金属耐受机理很复杂,需从多个角度阐述.但参与重金属应答的调节性基因研究较少,重金属响应调控网络并不清楚.microRNA(miRNA)是一类新型的调控基因表达的

【Abstract】 This paper focuses on the role of microRNAs(miRNAs) in response to cadmium(Cd) stress in rice.A number of Cd-responsive miRNAs in rice were identified by using microarray assay and quantitative Real-time PCR.The downstream targets were mainly regulatory genes which encoded transcription factors and protein kinases.These target genes were reported to be associated with metabolic processes and signal pathways.Promoter analysis showed that metal stress-responsive cis-elements tended to occur more frequently in the promoter regions of Cd-responsive miRNAs.These findings suggested that miRNAs played an important role in Cd tolerance in rice,and highlighted a heavy metal tolerance network involving miRNAs in plants.

【关键词】 microRNAcadmiummicroarrayresponseregulation
【Key words】 microRNAcadmiummicroarrayresponseregulation
【基金】 浙江省自然科学基金重点资助项目(Z3100327);国家自然科学基金资助项目(31170251,31071348);中国水稻研究所水稻生物学国家重点实验室资助项目(090102);2009年度浙江省研究生创新科研项目资助~~
  • 【文献出处】 生物化学与生物物理进展 ,Progress in Biochemistry and Biophysics , 编辑部邮箱 ,2011年12期
  • 【分类号】Q945.78
  • 【被引频次】20
  • 【下载频次】732
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