【摘要】 目的探讨少年和老年人鼻腔、鼻窦肿瘤的临床及病理组织学特点。方法收集入院诊治的30例少年和82例老年鼻腔、鼻窦肿瘤患者的临床资料,统计其性别、部位分布及病理构成比,观察其临床特征、病理组织学特点及治疗情况。结果①30例少年病例中,男∶女=1∶1,良性∶恶性=2.3∶1;原发于鼻腔的肿瘤有15例;原发于鼻窦的肿瘤15例,包括上颌窦6例、筛窦6例及蝶窦肿瘤3例。82例老年病例中,男∶女=1.8∶1,良性∶恶性=1∶1.2;原发于鼻腔的肿瘤有49例;原发于鼻窦的肿瘤33例,包括上颌窦19例、额窦3例、筛窦9例及蝶窦肿瘤2例;②少年鼻腔、鼻窦肿瘤总的构成比按组织来源排序如下:软组织>淋巴造血组织>骨及软骨组织>异位颅内组织肿瘤>上皮组织;老年组如下:上皮组织>软组织>骨及软骨组织>淋巴造血组织>异位颅内组织肿瘤;③良性肿瘤以手术治疗为主,恶性肿瘤采用以手术为主的综合治疗。结论少年和老年鼻腔、鼻窦肿瘤患者有明确的临床特征;肿瘤的部位构成比及不同部位肿瘤的发生特点均具有差异性;采用以手术为主的综合治疗。更多还原

【Abstract】 Objective To study the clinical and pathological characteristics of sinonasal neoplasms in children and elderly.Methods A cohort of hospitalized children and old patients confirmed by surgical pathology with sinonasal tumors were enrolled in this study.The characteristics,in terms of gender,origin,disease component ratio and therapeutic methods were reviewed.Results ① In this series of children,there were 15 males and 15 females and the ratio of benign to malignant tumors was 2.3∶ 1.15 neoplasms arose from the nasal cavity and 15 tumors arose from sinus.In the series of elderly patients,there were 53 males and 29 females and the ratio of benign to malignant tumors was 1∶ 1.2.49 tumors arose from the nasal cavity,while,33 neoplasms derived from sinus.② The disease component ratio of children decreased in order of soft-tissue,lymphohematopoietic tissue,bone and cartilaginous tissue,ectopic intracranial tumors,and epithelial tissue.The disease component ratio of the elderly decreased in order of epithelial tissue,soft-tissue,bone and cartilaginous tissue,lymphohematopoietic tissue,and ectopic intracranial tumors.③ Surgery is the main method for these benign tumors.And comprehensive treatment,in combination with other therapeutic methods,is the main strategy for malignant tumors.Conclusions Tumors in children and elderly from different parts of the nasal cavity and paranasal sinus have specific clinical and pathological characteristics.Comprehensive treatment is the main therapeutic method for these tumors.更多还原