【摘要】 目的探讨颅骨多处钻孔硬膜翻转并骨膜贴敷术治疗烟雾病的临床疗效。方法 19例烟雾病患者以缺血首发17例,出血首发2例,均行颅骨多处钻孔硬膜翻转并骨膜贴敷术,术后随访2~48个月,随访数据进行统计学分析。结果缺血型患者中TIA患者术后TIA未再发作,脑梗塞患者术后原有缺血症状改善或消失。2例出血型患者术后随访至今未发生再出血。10例患者术后行DSA复查,45个骨孔均有新生血管向颅内生长,新生血管来自脑膜中动脉和颞浅动脉。1例伴发动脉瘤患者术后DSA复查动脉瘤未显影。结论颅骨多处钻孔硬膜翻转并骨膜贴敷术治疗烟雾病简便、安全、有效。更多还原

【Abstract】 Objective To evaluate the therapeutic effectiveness of multiple burr hole surgery in conjunction with dural inversion and periosteum stitching in the treatment of moyamoya disease.Method This procedure was performed on 19 patients with moyamoya disease: 17 cases of the ischemic-type and 2 of the hemorrhagic-type.Follow-up time was 2 to 48 months,and data were statistically analyzed.Result After surgery,the original TIA symptoms did not come back.For ischemic-type patients,the ischemic symptoms were relieved and for hemorrhagic-type patients,no re-bleeding symptoms were found.Revascularization originating from the middle meningeal artery and the superficial temporal artery was observed in all the 45 cranial holes in 10 cases examined,as shown using DSA.The aneurysm in one case disappeared.Conclusion The multiple burr hole surgery in conjunction with dural inversion and periosteum stitching is a simple,safe and effective procedure for the treatment of moyamoya disease.更多还原