【摘要】 目的观察茶的摄入量即不同浓度茶饮对胃食管反流病的短期实时影响。方法采用前后自身对照、空白对照相结合的方法,以食管多通道腔内阻抗监测联合pH监测为工具,观察胃食管反流病患者午餐后饮用不同浓度茶饮后2 h观察时间段较早餐后不饮茶2 h观察时间段内各反流相关指标的异同。结果 A组饮茶叶3 g组(15例)与D组饮水组(12例)的食管酸暴露、反流次数、酸清除时间较未饮茶时前后自身比较无明显差异(P>0.05);B组饮茶叶6 g组(15例)与C组饮茶叶9 g组(15例)胃食管弱酸反流、无酸反流、混合反流、总反流次数、Z1通道酸清除时间较自身未饮茶时及A、D组有明显差异(P<0.05);C组食管pH<4时间百分比、酸反流、Z2、Z3通道酸清除时间较自身未饮茶时及A、B、D组有明显差异(P<0.05);A、B、C、D四组临床症状自身前后比较及饮茶后四组间比较均无明显差异(P>0.05)。结论 低浓度茶饮对胃食管反流无影响,高浓度茶饮可促进胃食管反流病患者出现更多的食管酸暴露和反流次数以及酸清除时间的延长。更多还原

【Abstract】 Objective To evaluate short real-time effect of different concentrations of tea on gastroesophageal reflux.Methods 57 patients were divided into four groups A,B,C and D.A randomized self-control together with blank-control trail was applied.Using combined esophageal multichannel intruluminal impedance and pH monitoring,patients drank different kinds of tea immediately after lunch,and they were tested during 2h after tea drinking and compared with 2h after breakfast without tea.Tested indexes included esophageal acid exposure time,gastroesophageal reflux episodes,acid clear time and symptoms.Results Group A(15 patients,3g tea) and group D(12 patients,drinking water) had no significant difference in all indexes between 2h after tea drinking and 2h without tea(P>0.05).In group B(15 patients,6g tea) and group C(15 patients,9g tea),weakly acidic reflux episodes,non-acid reflux episodes,mixed reflux episodes,total reflux episodes and acid clear time in the Z1 channel significantly increased after tea drinking compared with 2h without tea and groups A and D(P<0.05).In group C,percentages of pH<4 after tea drinking,acidic reflux episodes and acid clear time in Z2 and Z3 channels were all greatly increased after tea drinking compared with 2h without tea and groups A,B and D(P<0.05).No difference in clinical symptoms was found between pre-and post-drinking in each group and among the four groups(P>0.05).Conclusion Drinking weak tea has no effect on gastroesophageal reflux in a short time.Drinking strong tea may give rise to higher esophageal acid exposure,more reflux episodes and longer acid clear time.更多还原