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壳寡糖降血糖作用的临床观察研究
Clinical Observation on the Hypoglycemic Effect of Chitosanoligosaccharides
【摘要】 目的研究壳寡糖的降血糖作用。方法设计自身和组间对照方法,随机将自愿受试者分为研究组和对照组,分别服用壳寡糖或安慰剂30 d后,再次测定受试者空腹血糖和餐后2 h血糖。结果试食后,研究组多饮、多食、多尿等主要临床症状明显改善,空腹血糖下降(1.35±0.28)mmol/L,下降率(13.78±2.56)%;餐后2 h血糖下降(1.95±0.52)mmol/L,下降率(14.59±3.43)%。研究组空腹、餐后2 h血糖值自身比较及与对照组比较,均有极显著差异(P<0.01)。结论壳寡糖具有降血糖作用。
【Abstract】 Objective To study the hypoglycemic activity of chitosanoligosaccharides.Methods The design methods of self-control and inter-group comparison were adopted.The volunteers were randomly divided into test group and control group.After administration of chitosanoligosaccharides or placebo for 30 days,the fasting blood glucose and blood glucose two hours after meal of volunteers were measured again.Results After the test,the clinical symptoms of the test group were significantly improved.The fasting blood glucose decreased 13.78%(1.35±0.28 mmol/L);the blood glucose two hours after meal decreased 14.59 %(1.95±0.52 mmol/L).Compared with the control group,the fasting blood glucose and the blood glucose two hours after meal of the test group decreased significantly(P<0.01).Conclusion The results indicate that chitosanoligosaccharides can reduce the level of blood glucose in the patients with type Ⅱdiabetes mellitus.
- 【文献出处】 食品与药品 ,Food and Drug , 编辑部邮箱 ,2011年03期
- 【分类号】R587.1
- 【被引频次】22
- 【下载频次】426