【摘要】 目的探讨膀胱压监测与重症胰腺炎早期肠内营养治疗的关系。方法将41例重症胰腺炎患者随机分成实验组和对照组。实验组在给予肠内营养时进行膀胱压监测,根据膀胱压来决定给予肠内营养的时间和量;对照组在给予肠内营养时不进行膀胱压监测。比较两组病人治疗10d后APACHEII评分、血清白蛋白治疗前后变化以及两组病人感染发生率、死亡率、胃肠道反应等的差异。结果治疗前后实验组APACHEⅡ评分由(8.21±2.13)下降至(3.35±1.86),对照组APACHEⅡ评分由(8.13±1.98)下降至(3.91±2.12),两组差异有统计学意义(P<0.05);血清白蛋白实验组由(27.36±4.68)g/L上升至(34.32±4.40)g/L,对照组由(28.10±4.95)g/L上升至(32.11±5.13)g/L,两组差异有统计学意义(P<0.05)。实验组治疗后发生3例感染,2例腹胀,2例腹泻,1例死亡;对照组发生7例感染,11例腹胀,9例腹泻,2例死亡。结论重症胰腺炎患者在给予肠内营养时进行膀胱压监测可以有效降低APACHEII评分、感染发生率、胃肠道反应。更多还原

【Abstract】 Objective To investigate the relationship between intra-adominal pressure(IAP) measure and enteral nutrition treatment for severe acute pancreatitis(SAP).Methods Forty-one patients of SAP were randomized into two groups.Intra-adominal pressure measure was performed in group A,but not group B.APACHEII,ALB,infection,diarrhea,abdominal distension were both observed in two groups.Results In group A the APACHEII was declined to(3.35±1.86) from(8.21± 2.13),while group B was declined to(3.91±2.12) from(8.13±1.98,P<0.05).In group A ALB was raised to(34.32±4.40)g /L from(27.36±4.68)g /L,while group B was raised to(32.11±5.13)g /L from(28.10±4.95)g /L(P<0.05).Group A had 3 cases of infection,2 cases of diarrhea,2 cases of abdominal distension,1 death and group B had 7 cases of infection,9 cases of diarrhea,11 cases of abdominal distension,2 death after treatment.Conclusion Intra-adominal pressure measure has positive influence in SAP enteral nutrition treatment can reduce APACHEII,ALB,infection,diarrhea,and abdominal distension.更多还原