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深圳市耐多药肺结核67例临床特点研究

Clinical analysis of 67 multi-drug resistant tuberculosis cases in Shenzhen

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【作者】 吕建文杨应周吕德良吴清芳张玉华管红云车晓玲李明珍

【Author】 Lü Jian-wen,YANG Ying-zhou,Lü De-liang,et al.(Shenzhen Municipal Center for Chronic Disease Control,Shenzhen 518020,Guangdong,P.R.China)

【机构】 深圳市慢性病防治中心

【摘要】 目的探讨深圳市耐多药肺结核的临床特点。方法回顾性分析2009~2010年在深圳市慢性病防治中心诊治的67例耐多药肺结核的临床资料。结果深圳市67例耐多药肺结核患者男、女之比为1.5:1,平均年龄为33.2岁,外来流动人口占深圳市耐多药肺结核的比例达92.5%。病变范围达4个及以上肺野占61.2%,伴病灶空洞形成占71.6%,耐4~5种抗结核药者占49.3%,伴合并症者占63%,其中以肝功异常比例最高,占22.4%。结论应高度重视流动人口对大城市耐多药肺结核防治的影响,建议高耐药地区初治结核病患者治疗前常规进行痰培养和药敏试验,以早期发现、早期合理治疗耐药结核病。

【Abstract】 Aim To analyze the clinical features of multi-drug resistant tuberculosis in Shenzhen City.Methods The clinical data of 67 MDR-TB cases in Shenzhen during 2009~2010 was retrospectively analyzed.Results The male and female ratio of 67 MDR-TB cases in Shenzhen was 1.5: 1,the average age 33.2 years old,92.5% od the MDR-TB cases were among floating population.Lesions up to 4 and above of the lung field accounted for 61.2%,with cavitation lesions accounted for 71.6%,49.3% of the cases were resistant to 4 or 5 anti-TB drug,with complications accounted for 63% and 22.4% of them with abnormal liver function.Conclusions The work of MDR-TB control among floating population be strengthened and early detection and rational treatment are indicated with emphasis on the suputum culture and srug susceptibility tests.

【基金】 国家“十一五”重大科技专项“宝安区防治结核病规模化现场流行病学和干预的研究”(编号:2009ZX10003-018)
  • 【文献出处】 中国热带医学 ,China Tropical Medicine , 编辑部邮箱 ,2011年06期
  • 【分类号】R521
  • 【被引频次】4
  • 【下载频次】63
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