【摘要】 目的探讨N端脑钠肽前体(NT-proBNP)在心源性呼吸困难和肺源性呼吸困难诊断鉴别中的应用价值。方法回顾性分析入院治疗的124呼吸困难患者,包括心源性呼吸困难患者61例、肺源性呼吸困难患者63例,均应用罗氏心脏生物标志仪,检测两种呼吸困难患者静脉血NT-proBNP的浓度。结果心源性呼吸困难组患者NT-proBNP浓度明显高于非心源性呼吸困难组患者(P<0.001);心源性呼吸困难组NT-proBNP浓度在心功能不同级别间有统计学(P<0.001)。结论 NT-proBNP简便快捷、敏感性和特异性高,可作为鉴别急性呼吸困难患者的一个观察指标。心源性呼吸困难患者血清NT-proBNP水平明显较肺源性呼吸困难患者高。更多还原

【Abstract】 Objective To discuss the value of NT-proBNP in differential diagnosis of cardiac dyspnea and pulmonary dyspnea.Methods A retrospective analysis was conducted among 124 hospitalized patients with dyspnea,including 61 patients with cardiac dypnea and 63 patients with pulmonary dyspnea.All patients’ concentration of NT-proBNP was all measured with Roche cardiac biomarkers.Results The concentrations of NT-proBNP in patients with cardiac dyspnea were significant higher than that of non-cardiac dyspnea(P<0.001),the concentration of NT-proBNP in patients with cardiac dyspnea were significant different among different levels of heart function(P<0.001).Conclusions NT-proBNP can be used as a indicator in differential diagnosis of acute dyspnea because its convenience,highly sensitivity and specificity.The concentrations of NT-proBNP in patients with cardiac dyspnea are significant higher than that of pulmonary dyspnea.更多还原