Folium forsythia and fructus forsythiae are similar in its chemical component,folium forsythia is also used as drugs for clearing away heat and toxic material in folk-custom,great confusion is aroused when substituted extractive of fructus forsythiae for extractive of folium forsythia.We analyzed the cause of formation of this phenomenon,the relevant universal problems existed in the modernization of traditional Chinese medicine,and its research thoughtway is also explored.