【摘要】 目的:寻找婴幼儿反复喘息的危险因素,为预防和干预婴幼儿反复喘息发作提供理论依据。方法:以60例反复喘息的婴幼儿作为病例组,60例正常婴幼儿为对照组,采用向家长书面问卷调查方法询问各组婴儿既往病史、家族史、过敏史及婴幼儿喂养情况、生活条件等,并检测微量元素、免疫功能、过敏原。将30个因素作为变量进行赋值,进行数量化处理。应用单因素和多因素分析方法对资料进行分析。结果:多因素Logistic回归分析发现共有4个因素被选入回归方程,父母有哮喘病史(OR=4.969)、居住的城市(OR=3.054)、有过敏原阳性(OR=3.363)、有皮肤湿疹史(OR=3.180)。结论:父母有哮喘病史、有过敏原阳性、居住的城市、有皮肤湿疹史是导致婴幼儿发生反复喘息的关键危险因素。更多还原

【Abstract】 Objective:To find the risk factors of recurrent infant wheeze,so as to provide evidence for its prevention and intervention.Methods:60 infants with recurrent wheeze were chosen as case group;60 normal infants were chosen as control group in this study.All the enrolled patients were investigated using self-designed questionnaire about their case history,feeding,and allergic history of those infants and their parents,environmental factors and so on.At the same time,microelements,immunologic function and allergen were detected.Results:Four factors including parent asthma history(OR=4.969),living condition in urban area(OR=3.054),allergen positive reaction(OR=3.363)and atopic eczema history(OR=3.180) were selected for the multivariate regression analysis.Conclusion:The key risk factors of infant recurrent wheeze are parent’s asthma history,living in urban area,allergen positive reaction and atopic eczema history.更多还原