【摘要】 目的:探讨男性血清睾酮水平和代谢综合征(MS)的关联。方法:2008年11月至2009年2月对北京社区1006例30～60岁男性进行调查,分别检测腰围、血压、空腹血糖、甘油三酯、高密度脂蛋白胆固醇(HDL-C)、血清睾酮等。采用《2007中国成人血脂异常防治指南》推荐的MS诊断标准,分为MS组和非代谢综合征(NMS)两组,比较两组间各项指标水平差异,分析引起MS不同危险因素中血清睾酮水平以及血清睾酮和MS的相关性。结果:两组之间年龄无统计学差异(P>0.05),腰围、收缩压、舒张压、空腹血糖、甘油三酯、HDL-C、血清睾酮比较有显著性差异(P<0.001)。MS成分增多,血清睾酮水平则明显降低(P<0.01)。血清睾酮水平和年龄、腰围、收缩压、甘油三酯呈负相关(P<0.05)。结论:低血清睾酮水平在一定程度上能预示MS的发展。更多还原

【Abstract】 Objective:To investigate the association of the serum testosterone (T) level with metabolic syndrome (MS).Methods: We enrolled in this investigation 1 006 men aged 30-60 years in Beijing and obtained the data on their blood pressure (BP),waist circumference (WC),fasting blood glucose (FBG),serum triglycerides (TG),high density lipoprotein-cholesterol (HDL-C) and serum testosterone (T).The men were divided into an MS group and a non-MS (NMS) group based on The Chinese Adult Dyslipidemia Prevention Guide 2007.The results were compared and analyzed.Results: There was no statistically significant difference between the ages of the two groups (P >0.05).Systolic BP (SBP),diastolic BP (DBP),WC,FBG and TG were significantly higher,while serum T and HDL-C remarkably lower in the MS than in the NMS group (P <0.001).The serum T level was markedly decreased with the increase of MS components (P <0.01).Both Pearson’s correlation coefficients and multiple linear regression analyses showed that the serum T level was negatively correlated with age,WC,SBP and TG (P<0.05).Conclusion: Low serum T level may predict the development of MS in men.更多还原