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改良电抽搐治疗对精神分裂症患者记忆功能影响的临床研究

Effects of modified electroconvulsive therapy on memory of schizophrenia patients

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【作者】 钟海云禹海航陶长林赵峰谢曙光刘波王玉成宋来云

【Author】 ZHONG Haiyun,YU Haihang,TAO Changlin,ZHAO Feng,XIE Shuguang,LIU Bo,WANG Yucheng,SONG Laiyun.(Ningbo Kangning Hospital,Ningbo 315201,Zhejiang,China)

【机构】 宁波市康宁医院

【摘要】 目的探讨改良电抽搐治疗(MECT)对精神分裂症患者的记忆功能的影响。方法 60例精神分裂症患者给予MECT治疗,共8次。于治疗前后进行简明精神病量表(BPRS)、韦氏记忆量表各因子分及MQ值测评。结果总有效率为78.3%,BPRS平均减分率为51%;不同受教育程度和不性别间,治疗前后韦氏记忆量表各因子及MQ值差异均无统计学意义(均>0.05);治疗后韦氏记忆量表再认、联想因子分值较治疗前提高(均<0.05),但MQ差异无统计学意义(>0.05)。结论 MECT治疗对精神分裂症患者部分记忆执行功能有改善作用,但并没有整体提高患者的记忆功能。

【Abstract】 ObjectiveTo explore the effects of modified electroconvulsive therapy(MECT)on memory of schizophrenia patients and conduct a related factor analysis.Methods 60 schizophrenia patients were treated with MECT for 8times,and the tests of BPRS,Wechsler Memory Scale factors and MQ values before and after therapies were conducted.ResultsThe effective rate was 78.3%,the average reduction rate of BPRS was 51%;there were no significant differences between education and sex in the factors of Wechsler Memory Scale and MQ values(P>0.05).Wechsler Memory Scale recognition and association factor scores of Wechsler Memory Scale raised after therapies(P<0.05),but the MQ values before and after therapies showed no significant difference(P>0.05).ConclusionsMECT can partly improve the executive function of memory of schizophrenia,but there is no overall improvement of memory function in patients.MECT has a broad indications.

【基金】 宁波市医学科技计划项目(200542)
  • 【文献出处】 现代实用医学 ,Modern Practical Medicine , 编辑部邮箱 ,2011年06期
  • 【分类号】R749.3
  • 【被引频次】5
  • 【下载频次】96
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