【摘要】 目的:研究复尔康注射液对不同肿瘤细胞株的生长抑制作用。方法:以阿霉素为阳性对照,采用MTT法检测复尔康注射液对4种不同肿瘤细胞株的生长抑制作用。结果:复尔康注射液对人白血病HL-60、人红白血病K562、小鼠黑色素瘤B-16及人肝癌BEL-7402细胞的半抑制浓度(IC50)分别为42.80μg/ml、146.65μg/ml、463.37μg/ml和945.37μg/ml,在浓度为520μg/ml时,对4种细胞株的抑制率分别为89.12%、80.68%、63.40%和34.92%。结论:复尔康注射液在体外对4种肿瘤细胞株均具有明显的抑制作用,具有开发成抗癌新药的潜力。更多还原

【Abstract】 Objective:To study the inhibition effects of Fu’erkang Injection on different tumor cell strains.Methods:Adriamycin was used as positive control drug,and effects of Fu’erkang Injection were investigated on four kinds of tumor cell strains by methyl thiazolyl tetrazolium(MTT)assay.Results:The hemi-inhibitory concentration(IC50) of human leukemia cell strains HL-60,human leukemia cell strains K562,murine melanoma cell strains B-16 and human hepatoma cell strains BEL-7402 was 42.80μg/ml,146.65μg/ml,463.37μg/ml and 945.37μg/ml respectively,and the inhibition rates of tumor cell strains were 89.12%,80.68%,63.40% and 34.92% respectively when the concentration of Fu’erkang Injection was at 520μg/ml.Conclusion:Fu’erkang Injection has significantly inhibitory effect on four kinds of tumor cell strains,and has the potentiality to develop into a new drug.更多还原