【摘要】 目的研究肾脏疾病患者的血清HCY水平及其与6种肾病相关指标联合检测的临床意义。方法检测222例六类肾病患者血清HCY、Cyc、RBP、SCr、BUN及UA值,并探讨这些值与不同肾脏疾病的关系。结果慢性肾功能不全(非衰竭期)组、慢性肾功能衰竭组及糖尿病肾病组在全部6个指标的检测水平与对照组的差异均有统计学意义(P<0.05);除肾病综合征组及慢性肾炎组,其他疾病组的血清HCY水平与对照组的差异有统计学意义(P<0.05);组、组与组相比,其HCY水平的差异有统计学意义。结论 HCY与6种肾病相关指标联合,能检测出所有六类肾脏疾病,对肾脏疾病的鉴别及疾病严重程度的判断有一定的参考意义。更多还原

【Abstract】 Objective To evaluate the clinical significance of the combined examination of serum HCY and the other six kidney-related indicators in patients with renal disease.Methods Serum HCY,Cyc,RBP,SCr,BUN and UA values were determined in 222 patients with six types of renal disease and to discuss the relationship between different parameters and the kidney diseases.Results Compared with normal control group the content of all six indicators in chronic renal insufficiency(non-failure stage) group,chronic renal failure group and diabetic nephropathy group were statistically different(P<0.05).Except for nephrotic syndrome group and chronic nephritis group,compared with normal control group serum HCY in other renal disease groups were statisticaly different(P<0.05).Compared to group Ⅲ,there were significant differences in the serum HCY of group Ⅰ and Ⅱ.Conclusions Combined examination of serum HCY and six kidney-related indicators can detect all six types of renal disease,and has reference significance for identification and severity judgement of the renal diseases.更多还原