【摘要】 目的探讨老年急性脑梗死后脑氧摄取分数（OEF）变化及临床价值。方法将58例老年脑梗死患者根据格拉斯哥昏迷评分（GCS）分为重症组32例,非重症组26例,通过颈内静脉置管采血检测颈内静脉血氧饱和度（SjvO₂）,同时检测脉搏血氧饱和度,并计算OEF。比较2组SjvO₂和OEF,并分析两者与GCS、格拉斯哥匹斯堡昏迷评分（GCS-P）、格拉斯哥预后评分（GOS）的相关性,以及OEF对预后的预测价值。结果与非重症组比较.重症组患者SjvO₂明显升高,OEF明显降低,差异有统计学意义（P<0.01）。SjvO₂与GCS、GCS-P、GOS呈负相关,OEF与GCS、GCS-P、GOS呈正相关（P<0.01）。OEF≤30%患者的预后不良发生率明显高于OEF>30%患者（P<0.01）。结论 OEF可作为老年颈内动脉系统急性脑梗死后,评估脑功能损伤程度和预测预后的重要指标。更多还原

【Abstract】 Objective To investigate the changes of cerebral oxygen extraction fraction（OEF） following acute cerebral infarction and its clinical value in old patients.Methods Fifty-eight old patients with acute cerebral infarction of carotid artery system were divided into two groups:severe group（GCS≤8,32 cases） and non-severe group（GCS>8,26 cases）.Blood samples were obtained through jugular catheter and then jugular vein blood oxygen saturation（SjvO₂） was measured. Simultaneously pulse blood oxygen saturation was measured and OEF was calculated.SjvO₂ and OEF were compared between two groups.The relationships of the two parameters with GCS. GCS-P and GOS were analyzed.The value of OEF for predicting prognosis was investigated.Results SjvO₂ was significantly higher in severe group than in non-severe group（P<0.01）.while OEF was significantly lower in severe group than in non-severe group（P<0.01）.SjvOv was negatively correlated with GCS,GCS-P and GOS（P < 0.01）,while OEF was positively correlated with GCS,GCS-P and GOS（P < 0.01）.Unfavourable prognosis incidence was higher in the patients with OEF≤30%than in those with OEF>30%（P <0.01）.Conclusions For old patients with acute cerebral infarction of carotid artery system,OEF is a valuable parameter for evaluating degree of cerebral function injury and predicting prognosis.更多还原