【摘要】 目的探讨复方樟柳碱对增生期糖尿病性视网膜病变(DR)全视网膜激光光凝治疗后视神经缺血的疗效。方法对36例(57只眼)增生期DR全视网膜激光光凝治疗后视神经缺血患者,应用复方樟柳碱颞浅动脉旁注射,观察其视力、视野等视功能变化。14d为1个疗程,分别于治疗后1、2、3、6、12个月观察视力、视野变化。通过显效、有效、无效3个标准判断疗效。结果随诊5～12个月,其中1例(1只眼)在治疗期间出现视网膜中央动脉阻塞导致视力明显下降,1例(1只眼)治疗期间出现注射部位皮肤湿疹样改变终止治疗,其余患者治疗后2个月内视力均有不同程度的提高,视野较治疗前范围扩大。有效96.5%,显效56%,无效3.5%。结论增生期DR激光治疗后应重视视神经缺血状态的发生;及时应用复方樟柳碱可有效减轻视神经缺血,保护糖尿病患者的视功能。更多还原

【Abstract】 Objective To observe the curtive effect observation of compound anisodine on ischemia of optic nerve after pan-retinal photocoagulation of proliferative diabetic retinopathy.Methods 36 cases(57 eyes) of ischemic optic neuropathy after vitretomy or Post pan-retinal photocoagulation of proliferative diabetic retinopathy ,evaluating visual field、visual acuity after compound ansiodine was injected subcutaneously around superficial temporal artery . Treated with 2ml compound ansiodine was injected subcutaneously around superficial temporal artery once for 14d,observe visual acuity and visual field after treatment 1、2、3、6、12 months,judging curative effect by special effect、validand invalid.Results Follow-up to 5 to 12 months,all the visual acuity of the patients were increased and the extent of visual field enlargement,visual acuity increased apparente after 2 months after treatment besides 1 case(1 eye),who had happened central retinal atery occlusion lead to visual acuity decreased obviously,and 1 case (1 eye)was stopped treating for the skin at the injection site emerge eczema-like changes. the effect rate reached 96.5%,special effect 56%,invalid 3.5%.Conclusion Highly state of affairs of optic nerve ischemia after surgery and retinal photocoagulation of proliferative diabetic retinopathy should be thought.Apparente compound anisodine can lighten optic nerve ischemia,protected visual function and ischemic injury of retina blood vessel in diabetic mellitus patients.更多还原