【摘要】 目的:探讨莫西沙星短程疗法治疗慢性阻塞性肺疾病急性加重期(AECOPD)的疗效及安全性。方法:80例AECOPD患者随机分成试验组和对照组各40例,试验组及对照组均采用莫西沙星每天静脉滴注0.4g,试验组疗程为5d,对照组疗程为10d。对2组患者的临床疗效、细菌清除率及不良反应进行观察和比较。结果:试验组的临床疗效、细菌清除率与对照组相似,差异无统计学意义(P>0.05),而不良反应发生率小于对照组,差异有统计学意义(P<0.05)。结论:莫西沙星短程疗法对AECOPD具有良好的治疗效果。更多还原

【Abstract】 Objective:To evaluate the efficacy and safety of moxifloxacin short-course treatment in patients with acute exacerbations of chronic obstructive pulmonary disease(AECOPD).Methods:Atotal of 80 patients were randomly into study group and control group,40 cases in each group.Both a groups were given moxifloxacin intravenously 400 mg once daily.The course of therapy was 5 days for study group and 10 days for control group.The clinical effect of the two groups were observed and compared.Results:The clinical success and bacterial eradication rates were similar between the study group and the control group(all P>0.05),while the adverse effect rates was occurred less in study group than in control group(P<0.05).Conclusions:Short-course treatment of moxifloxacin is effective and safe in the therapy of AECOPD.更多还原