【摘要】 目的探讨多发性硬化(MS)患者生活质量的影响因素。方法应用日常生活活动能力(ADL)量表对99例确诊的MS患者出院时进行神经功能评价,运用单因素分析和多因素Logistic回归分析方法对MS患者残疾相关的影响因素进行分析。结果本组患者中女性、病程>16年、发作≥3次、MRI示脊髓病灶及首发症状为脊髓受累与神经功能严重缺损相关(P<0.05~0.01)。多因素Logistic回归分析显示,MRI示脊髓病灶和发作次数与患者残疾程度相关(P<0.05~0.01)。结论脊髓病灶及发作次数是影响MS患者生活质量的独立危险因素。更多还原

【Abstract】 Objective To explore the influential factors to quality of life in patients with multiple sclerosis(MS).Methods The neurological function of 99 diagnosed MS patients were evaluated by Activities of Daily Living(ADL) scale at discharge.The influential factors of related disablement were analyzed with unvaried analysis and multivariate logistic regression analysis.Results In this group,female,MS duration>16 years,number of attack≥3 times,lesion in the spinal cord showed by MRI,and spinal cord symptoms as initial symptoms were significantly associated with severe neurological disfunction(P<0.05-0.01).The multivariate logistic regression analysis showed that the lesion in spinal cord showed by MRI and number of attack were associated with the severity of disability(P<0.05-0.01).Conclusion The lesion in spinal cord and number of attack are the independent influential factors to quality of life in MS patients.更多还原