【摘要】 目的:了解住院精神分裂症患者糖耐量减低(IGT)的发生率及其相关因素。方法:对上海市普陀区精神卫生中心住院的精神分裂症患者作调查,测定其代谢指标,IGT采用《中国2型糖尿病防治指南2007》诊断标准。结果:共入组286例,住院精神分裂症患者IGT的发生率为27.3%(78/286),男性为27.6%(53/192);女性为26.6%(25/94)。年龄、三酰甘油、收缩压、舒张压、是否服用氯氮平与IGT患病率有关(P<0.05)。Logistic回归发现三酰甘油、年龄及收缩压为IGT的患病危险因素。结论:住院精神分裂症患者中存在较高的IGT发生率,应予以关注。更多还原

【Abstract】 Objective:To investigate the occurrence of impaired glucose tolerance in schizophrenic inpatients and its relative factors.Method:286 schizophrenic inpatients treated in Shanghai Putuo Mental Health Center were investigated.Metabolic indexes were measured and diagnosed based on the criteria of impaired glucose tolerance of the Prevention of type 2 diabetes in China Guide 2007.Results:The impaired glucose tolerance rate in the total subjects,male and female patients was 27.3%(78/286),27.6%(53/192) and 26.6%(25/94) respectively.Age,triglyceride,systolic blood pressure,diastolic blood pressure and clozapine use were correlated with the impaired glucose tderance(IGT) occurrence(P<0.05).Logistic regression analysis indicated that triglyceride,age and systolic blood pressure were risk factors for IGT.Conclusion:Impaired glucose tolerance occurs in many schizophrenic inpatients,which should be paid attention to.更多还原