【摘要】 目的探讨320排CT和二维超声心动图对冠心病心功能评价的相关性及320排CT在冠心病左心室功能评价中的价值。资料与方法搜集2009年9月至12月间行320排CT冠状动脉造影检查和二维超声心动图的冠心病患者45例,其中男29例,女16例,平均年龄(64±9)岁。利用冠状动脉CT血管造影(CTA)的原始数据进行多期相重建,在专用心功能分析软件(Vitrea FX)中进行左心功能分析,利用Simpson法计算出左心功能指标:舒张末期容积(EDV)、收缩末期容积(ESV)、每搏输出量(SV)和射血分数(EF)。结果 320排CT与二维超声心动图两种方法的冠心病心功能指标差异无统计学意义(P>0.05),两种方法的冠心病心功能指标:EDV、ESV、SV和EF相关性高,相关系数分别为0.867、0.791、0.723和0.674。结论 320排CT在冠心病左心功能定量评价方面结果准确、可靠,与二维超声心动图测得的心功能指标差异无统计学意义,两种方法各指标间相关性高。320排CT心功能分析与冠状动脉造影检查协议相同,收缩末期和舒张末期图像可以通过回顾性心电门控冠状动脉CTA数据获得,心功能分析包含于冠状动脉检查中,患者无需接受更多的辐射剂量和对比剂。更多还原

【Abstract】 Objective To assess the value of 320-CT in evaluating left ventricular function in patients with coronary heart disease,compared with 2D-echocardiography.Materials and Methods Forty-five patients(16 females,29 males with mean age of 64±9)with coronary heart disease were studied with 320-CT and 2D-echocardiography.Ten series of images were reconstructed at every 10% throughout the cardiac cycle.Left ventricular function was measured in diastolic and systolic phase using circulation software of 320-CT(Vitrea FX).The end-diastolic volume(EDV),end-systolic volume(ESV),stroke volume(SV),and ejection fraction(EF) were calculated using Simpson method.Results The measurements of EDV,ESV,SV,and EF obtained by 320-CT were closely correlated with those obtained by 2D-echocardiography.There was no statistically significant difference of the measurements between two methods(P>0.05).The correlation coefficients were 0.674-0.867(P﹤0.05).Conclusion Compared with 2D-echocardiography,left ventricular function indexes obtained by 320-CT were accurate,the correlation of the results was quite well.Left ventricular function assessments were carried out complementary to coronary CTA,and the imaging protocols are the same.Images of end-systolic and end-diastolic phases can be retrospectively produced using ECG gating without additional radiation exposure or administration of contrast material.更多还原