【摘要】 目的探讨弹簧式自动切割针胸膜活检在良恶性胸腔积液诊断的临床应用价值。方法对2006年1月~2009年5月对279例原因不明的胸腔积液患者随机分为观察组肺活检针(意大利制造的弹簧式自动切割针)168例和对照组常规胸膜活检针(上海制造的改良Cope钝头胸膜活检针)111例,行针刺胸膜活检并对结果进行回顾性分析。结果弹簧式自动切割针观察组取材成功率与活检的确诊率均与对照组相似(95.2%对95.5%,35.1%对36.9%)。结核性病变阳性率与恶性病变阳性率在观察组均高于对照组(31.4%对30.6%,44%对41.9%)。并发症观察组低于对照组(5.4%对20.7%)。结论使用弹簧式自动切割针较使用改良Cope钝头胸膜活检针行针刺胸膜活检,既可提高诊断率又能显著减少并发症发生,值得推广使用。更多还原

【Abstract】 Objective To evaluate the clinic value of pleural biopsy with spring-loaded auto-cutting needle in the etiological diagnosis of benign and malignant pleural effusion.Methods 279 unexplained pleural effusion patients from 2006(January) to 2009(May) were randomly divided into two groups and manipulated the pleural biopsy with different needles: the observation group(168 patients) using spring-loaded auto-cutting needle and the control group(111 patients) using the improved Cope blunt pleural biopsy needle made in Shanghai.The results of the two different methods were recorded.Results The achievement ratio and diagnosed rates of pleural biopsy in two groups was similar(95.2% to 95.5%,35.1% to 36.9%).Positive rate of tuberculosis-pathologic and malignant pathologic change in the observation group were higher than that in the control group(31.4% to 30.6%,44% to 41.9%).Complication rate in the observation group was lower than that in the control group(5.4% to 20.7%).Conclusion In a word,tit is worth recommendation that with spring-loaded auto-cutting needle to operate pleural biopsy can not only improve rate of pathologic diagnosis,but also significantly reduce the rate of complications in pleural biopsy.更多还原