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鼻咽癌眼部症状的临床研究

Study about eye complication of nasopharyngeal carcinoma

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【作者】 练兵王继群张伟军山艳春

【Author】 LIAN Bing1 WANG Jiqun2 ZHANG Weijun3 SHAN Yanchun2(1Department of Otolaryngology-Head and Neck Surgery,the First Affiliated Hospital of Jinan University,Guangzhou,510630,China;2The Medical College of Jinan University;3Department of Radiation,Gugangzhou City Cancer Hospital)

【机构】 暨南大学附属第一医院耳鼻咽喉头颈外科暨南大学医学院广州市肿瘤医院放疗科

【摘要】 目的:探讨鼻咽癌眼部症状的临床表现、影像学及病理学诊断及相互对应的关系。方法:选择562例鼻咽癌患者,对其中82例有眼部症状者的临床表现、病理诊断和CT表现进行回顾性分析。结果:有眼部症状者占全部鼻咽癌患者的14.6%(82/562)。累及左眼36例,右眼37例,双眼9例。来自广东省65例,其余5省市共17例。以视朦和复视为主有9种眼部表现。影像学CT显示颅底骨质破坏及颅内侵犯40例,侵犯眼眶6例,眶内转移2例(左眼),累及鼻-鼻窦12例,咽旁间隙68例,茎突内侧软组织49例。结论:鼻咽癌眼部症状具有多样化和复杂性,在临床工作中容易误诊或漏诊,应引起眼科临床医生的足够重视。

【Abstract】 Objective:To explore the eye complication of nasopharyngeral carcinoma(NPC),to analysis the clinical manifestation,CT characteristics and pathological diagnosis of eye complications of NPC and to provide the base for early diagnosis of NPC.Method:To retrospectively study of 82 cases eye complications in 562 cases NPC,to study their clinical manifestation,CT characteristics and pathological diagnosis.Result:The clinical studies showed that eye complication cases were occurred in 82 cases of 562 NPC cases(14.6%).Thirty-six cases in left and 37 cases in right eye,9 cases in bilateral eyes.Sixty-five cases came from Guangdong,while the others 17 cases come from 5 provinces.There were 9 kinds of eye manifestation.CT appearances: 40 cases suffered from skull base distracted,6 cases with orbit involved,2 cases(in left eyes) with orbit metastasis,12 cases with nose-sinus involved,68 case with parapharyngeal space involved,49 cases with soft issue in wall of styloid process involved(there were many kind of shows in the same case,so the data were repeated in these cases).Conclusion:There were multiplicity and complexity in eye complication of NPC.Ophthalmologists should think highly of these cases.

【基金】 澳门特别行政区科学技术发展基金资助;澳门医学科技研究协会与广州暨南大学医学院科研合作项目(No:029/2009/A)
  • 【文献出处】 临床耳鼻咽喉头颈外科杂志 ,Journal of Clinical Otorhinolaryngology Head and Neck Surgery , 编辑部邮箱 ,2011年24期
  • 【分类号】R739.63
  • 【被引频次】1
  • 【下载频次】131
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