【摘要】 目的探讨系统性红斑狼疮(SLE)患者血清中白细胞介素-6(IL-6)、IL-10、肿瘤坏死因子-α(TNF-α)的水平变化和意义。方法分别用放射免疫分析和酶联免疫吸附试验(ELISA)对26例SLE患者IL-6I、L-10、TNF-α进行检测,并与20例健康者作比较。结果 SLE患者IL-6I、L-10和TNF-α水平明显高于健康组,差异具有统计学意义(P<0.01)。结论检测SLE患者血清IL-6I、L-10、TNF-α水平的变化对SLE患者的临床诊断和临床观察有临床价值。更多还原

【Abstract】 Objective To explore the clinical signficance of the changes of serum IL-6,IL-10 and TNF-α in patients with SLE.Methods The level of TNF-α was detected by RIA,and levels of IL-6 and IL-10 were detected by ELISA in 26 patients with SLE and 20 controls.Results The levels of serum IL-6,IL-10,TNF-α in those patients with SLE were higher than those if control,the result was significantly different(P<0.01).Conclusion Detection of the changes in serum IL-6,IL-10 and TNF-α levels may have some clinical values in the clinical diagnosis and observation in patients with SLE.更多还原