【摘要】 目的了解广州地区育龄妇女和妊娠妇女TORCH感染状况,探讨不良妊娠与TORCH感染的关系以及不同季节TORCH感染的流行情况。方法采用酶联免疫吸附试验对2009年6月至2010年6月的600例育龄妇女和2 813例妊娠妇女(包括2 677例健康妊娠和136例不良妊娠)进行TORCH-IgM抗体检测。结果妊娠妇女巨细胞病毒(CMV)-IgM的阳性率为5.76%,远远高于其他病原体的IgM阳性率,差异有统计学意义(P<0.05);妊娠妇女的TORCH-IgM总阳性率(11.13%)高于育龄妇女的总阳性率(6.50%),差异有统计学意义(P<0.05);不良妊娠妇女所有TORCH项目的 IgM阳性率均显著高于健康妊娠妇女,差异有统计学意义(P<0.05);春、夏季TORCH-IgM总阳性率和纯弓形体(TOX)、CMV、单纯疱疹病毒(HSV)Ⅰ及HSVⅡ的IgM阳性率明显高于秋、冬季,差异均有统计学意义(P<0.05),而风疹病毒(RUV)-IgM阳性率冬、春季显著高于夏、秋季,差异均有统计学意义(P<0.05)。结论广州地区妊娠妇女CMV阳性率高于妊娠妇女其他病原体阳性率,也高于育龄妇女CMV阳性率;妊娠妇女TORCH总阳性率高于育龄妇女;TORCH系列病原体与不良妊娠及季节密切相关。更多还原

【Abstract】 Objective To investigate the rates of TORCH(toxopasma,rubella virus,cytomegalo virus,herpes virus) infection in child-bearing-age and pregnant women in Guangzhou and explore the relationship among abnormal pregnancy,different seasons and the TORCH infection.Methods We detected the TORCH-IgM from Jun 2009 to Jun 2010,serum samples from 600 child-bearing-age women and 2 813 pregnant women(2 677 with normal pregnancy and 136 with abnormal pregnancy) were tested by ELISA.Results The positive rate of CMV-IgM in the pregnant women was 5.76%,which was higher than that of other pathogens(P<0.05).The total positive rate of TORCH-IgM in pregnant women(11.13%) was significantly higher than the rate in child-bearing-age women(6.50%).All the TORCH-IgM antibodies had significant difference between the abnormal pregnancy and normal pregnancy(P<0.05).The total positive rate of TORCH-IgM and the positive rate of TOX,CMV,HSVⅠ,HSVⅡ-IgM in spring and summer were higher than the ones in autumn and winter(P<0.05).The positive rate of RUV-IgM in spring and winter was higher than the one in summer and autumn(P<0.05).Conclusion Guangzhou area has a high CMV infection rate in pregnant women.The rate of TORCH infection in pregnant women is higher than the rate in child-bearing-age women.The pathogens of TORCH are closely related to abnormal pregnancy and seasons.更多还原