【摘要】 目的分析降钙素原(PCT)检测在儿童血液细菌感染所致败血症中的独特意义。方法回顾性分析两年内就诊的46例败血症患儿PCT、C反应蛋白(CRP)和白细胞(WBC)的检测结果,讨论PCT在检测过程中的敏感性、特异性及与疾病进展的相关性。结果在感染早期,PCT检测的阳性率和CRP无明显差异,但高于WBC检测和细菌培养的敏感性;随着血液感染被控制,PCT转阴的时间最短,与疾病的转归关系更为密切。结论 PCT在儿童败血症诊断中具有采样方便、检测快捷、灵敏度高、特异性强的优点,可作为协助诊断儿童败血症的优先指标。更多还原

【Abstract】 Objective To analyze the particular significance of serum procalcitonin detection in child septicemia caused by blood bacterial infection.Methods To retrospectively analyze the detection results of PCT,CRP and WBC in 46 children cases of septicemia in our hospital within two years.To discuss the sensitivity,specificity of PCT and its relativity to the disease progress.Results In the early stage of infection,the positive rate of PCT and CRP had no significant difference.But the sensitivity of PCT was higher than that of WBC counting and germiculture.Along with the bloodstream infections being controlled,the time of PCT converting to negative was shortest,which was closely related with the disease outcome.Conclusion In diagnosing child septicemia,PCT has the advantages of convenient sampling,rapid assay,high sensitivity and better specificity,which may be used as the priority index for assisted diagnosis of child septicemia.更多还原