【摘要】 目的探讨血清降钙素原(procacitonin,PCT)对危重患者感染诊断及其预后判断中的临床价值。方法将重症监护病房(intensive care unit,ICU)危重患者分为重症感染组、一般感染组、对照组,应用荧光酶免疫法定量检测其血清PCT水平,同时采集血液进行细菌培养,部分病例采集痰、尿、创面分泌物等标本作细菌培养,并观察其预后。结果重症感染组、一般感染组分别与对照组比较PCT浓度有显著增高(P<0.05);重症感染组与一般感染组比较,其PCT阳性率与细菌培养阳性率都明显升高,差异有统计学意义(P<0.05);PCT浓度与患者的预后密切相关,一般感染组较重症感染组预后效果良好。结论血清PCT对危重患者感染诊断及判断患者预后具有重要的指导性意义。更多还原

【Abstract】 Objective To evaluate the clinical value of procalationin(PCT) to the diagnosis of infections and prognosis in the critical patients.Methods PCT was measured for patients in the intensive care unit of our hospital,who were divided into severe infection group,general infection group and non-infection group.Results The levels of PCT in severe infection group were significantly higher than those in noninfection group.The positive rate of PCT was significantly higher than that of hemocultures in severe group and general infection group.There was significant correlation between serum PCT and prognosis.Conclusion PCT has important guiding significance for the diagnosis of infections and prognosis evaluation in the critical patients.更多还原