【摘要】 目的观察雄激素在重症感染病人中的临床疗效、免疫细胞变化。方法将重症感染病人随机分为对照组与治疗组,治疗组在对照组的基础上加丙酸睾酮50mg/d共7d,观察两组患者治疗前后临床表现变化、细菌学变化、血CD3+、CD3+CD4+、CD4/CD8变化。结果治疗组有效病例数多于对照组,P<0.05有显著统计学意义。血CD3+CD4+、CD4/CD8治疗组较对照组均高,P<0.05有显著统计学意义。结论重症感染病人雄激素短期治疗有一定疗效,且对细胞免疫有一定的调节作用。更多还原

【Abstract】 Objective To observe the clinical effect and immune cells changes of male hormones in intensive care unit patients.Methods The intensive infection patients can be divided into contrast group and treatment group in random.The treatment group use testosterone propionate 50mg per day in the basis of contrast group,which last seven days.Then observe the clinical changes,bacteriology changes and blood CD3+、CD3+CD4+、CD4/CD8 changes after treatment of patients.Results The effective cases in treatment group is significantly higher than the contrast group.P<0.05 is of remarkable statistical significance.Blood CD3+、CD3+CD4+、CD4/CD8 in treatment group is also higher than the contrast group.P<0.05 is of remarkable statistical significance.Conclusion Male hormones have some treatment effect to intensive infection patients,and regulating effect to cells immunity.更多还原