【摘要】 目的评估经皮胆道支架联合支架旁125Ⅰ粒子条植入治疗恶性胆道梗阻的疗效。方法选取28例恶性胆道梗阻患者,行经皮胆道支架联合支架旁125Ⅰ粒子条植入,疗效评价标准:统计手术成功率、临床症状缓解情况、术后并发症以及生存期。结果所有患者手术均获得成功,未发生与手术相关严重并发症,术后梗阻性黄疸症状逐步改善,术后1个月血清胆红素水平均较术前明显下降(P<0.01);中位生存期为4.7个月,平均生存期为5.7个月。结论经皮胆道支架联合支架旁125Ⅰ粒子条植入治疗胆道梗阻安全有效,但远期效果仍需进一步观察。更多还原

【Abstract】 Objective To evaluate the therapeutic efficacy of linear 125Ⅰ seeds strand implantation combined with biliary stenting in treating malignant biliary obstruction.Methods Linear 125Ⅰ seeds strand implantation combined with biliary stenting was carried out in 28 patients with malignant biliary obstruction.The technical success rate,the clinical efficacy,the postoperative complications and the survival rate were analyzed.Results Both biliary stenting and 125Ⅰ seeds strand implantation were successfully accomplished in all patients.No serious complications occurred.After the procedure the biliary obstruction symptoms were markedly improved and the bilirubin level was significantly reduced(P < 0.01).The median survival period and mean survival period were 4.7 months and 5.7 months,respectively.Conclusion For the treatment of malignant biliary obstruction,linear 125Ⅰ seeds strand implantation together with biliary stenting is safe and effective although its long-term efficacy needs to be further studied.更多还原