【摘要】 目的探讨血清微量元素铁锌铜及免疫球蛋白与复发性阿弗他溃疡(recurrent aphthous ulcer,RAU)的关系。方法 RAU患者102例作为病例组,选择年龄、性别相匹配的86例健康人群作为对照组,两组分别采集空腹静脉血,用全自动生化分析仪测血清铁、锌、铜含量,用特种蛋白检测仪测血清免疫球蛋白水平,并与正常值比较。结果病例组血清铁的缺乏率14.71%,高于对照组(5.81%),差异有统计学意义(P=0.049);两组间血清锌、血清铜的缺乏率均没有统计学差异(均有P>0.05)。两组间血清免疫球蛋白水平均没有统计学差异。结论 RAU病因复杂,微量元素缺乏、免疫球蛋白异常证据不足,还需进一步做大样本研究。更多还原

【Abstract】 Objective To study the relationship of Iron,Zinc-Copper,immunogloblin in serum with recurrent aphthous ulcer(RAU).Methods 102 patients with RAU and 86 healthy controls were recruited.The age and sex were matched in two groups.The concentration of Iron,Zinc,-Copper,immunogloblin were measured in serum by Automatic Biochemistry Analyzer and Special Protein Detector respectively.Results The serum iron of RAU group was more deficient(14.71%) than the control(5.81%),there was significant difference between two groups(P=0.049).There was no significant difference of the Zinc,-Copper and immunoglobulin between the two groups(both P>0.05).Conclusions The RAU etiology was complicated.The evidence of minor elements deficiency and immunogloblin abnormality are insufficient.Further study with large sample size are needed.更多还原