【摘要】 诱导型多能干细胞(iPSc)具备胚胎干细胞的分化潜能,同时又回避了伦理问题,因此具有广泛且重要的临床应用价值。然而,目前iPS技术仍然存在致癌性、效率低等一系列问题。针对这些亟待解决的问题,本文综述了最近几年国内外在iPS细胞研究领域中的发展现状及研究方法,并探讨该领域中急需解决的问题和发展前景,以为诱导性多功能干细胞的研究提供一定的借鉴。更多还原

【Abstract】 Induced pluripotent stem cells(iPSCs),having differentiation potential of the embryonic stem cell while avoiding the ethical issues,has wide and important clinical applications.However,there remain many problems to be solved for iPSCs technology itself,such as carcinogenicity,low efficiency of generation and so on.In order to solve the existent problems,the development and research methods in the international field of iPSCs,and the urgent problems and development prospects were reviewed here,so as to provide references for the future researches in this aspect.更多还原