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依达拉奉联合奥扎格雷钠治疗进展型脑梗死的疗效及对神经功能缺损和日常生活能力的影响
United ozagrel edaravone for treatment of 45 patients with progressive cerebral infarction
【摘要】 目的观察依达拉奉联合奥扎格雷钠治疗进展型脑梗死的疗效及对神经功能缺损和日常生活能力的影响。方法选择急性进展性脑梗死患者90例,随机分为依达拉奉与奥扎格雷钠联合治疗组和奥扎格雷钠单药对照组各45例,治疗疗程共14d。在治疗前、后进行神经功能缺损程度(the nantional institute of health strokescale,NIHSS)、日常生活活动能力(activities of daily living,ADL)和临床疗效的评定。结果治疗组神经功能损害程度评分显著下降,临床疗效显著高于对照组(P<0.05)。两组均无不良反应。结论依达拉奉联合奥扎格雷钠治疗进展性脑梗死有显著疗效,无明显不良反应。
【Abstract】 Objective To observe the joint ozagrel edaravone treatment of progressive cerebral infarction.Methods Totally 90 patients with acute progressive cerebral infarction were randomly divided into the edaravone and ozagrel ozagrel combination therapy group and monotherapy group of 45 cases,the treatment course of 14 days.Before treatment,after the degree of neurological deficits(the nantional institute of health stroke scale,NIHSS),ADL(activities of daily living,ADL) and clinical assessment of efficacy.Results The neurological severity score decreased significantly,clinical efficacy was significantly higher(P<0.05).There were no adverse reactions.Conclusions The combined ozagrel edaravone treatment of progressive cerebral infarction has a significant effect,no significant adverse reactions.
- 【文献出处】 医药论坛杂志 ,Journal of Medical Forum , 编辑部邮箱 ,2011年07期
- 【分类号】R743.3
- 【被引频次】5
- 【下载频次】45